Literature summary for 3.1.1.47 extracted from

Yamaguchi, N.; Koizumi, H.; Aoki, J.; Natori, Y.; Nishikawa, K.; Natori, Y.; Takanezawa, Y.; Arai, H.
Type I platelet-activating factor acetylhydrolase catalytic subunits over-expression induces pleiomorphic nuclei and centrosome amplification (2007), Genes Cells, 12, 1153-1161.

Search for more literature for 3.1.1.47

Cloned(Commentary)

Cloned (Comment)	Organism
overexpression of the catalytic subunits, especially alpha2, in cultured COS cells induced dramatic phenotypical changes including nuclear shape change, centrosomal amplification and microtubule disorganization	Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Mus musculus	the PAF-AH (I) catalytic subunits induces centrosomal amplification and microtubule disorganization by disturbing intracellular localization of LIS1 (a causative gene product for type I lissencephaly)	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	the PAF-AH (I) catalytic subunits induces centrosomal amplification and microtubule disorganization by disturbing intracellular localization of LIS1 (a causative gene product for type I lissencephaly)	Mus musculus	?	-	?

Synonyms

Synonyms	Comment	Organism
type I platelet-activating factor acetylhydrolase	-	Mus musculus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)