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Literature summary for 3.1.1.47 extracted from
- Platelet-activating factor (PAF)-like activity, localization of PAF receptor (PAF-R) and PAF-acetylhydrolase (PAF-AH) activity in bovine endometrium at different stages of the estrous cycle and early pregnancy (2001), Prostaglandins, 65, 125-141.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Bos taurus | 5829 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 45000 | - |
x * 45000, plasma and endometrial enzyme, SDS-PAGE | Bos taurus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O | Bos taurus | i.e. platelet-activation factor | 1-alkyl-sn-glycero-3-phosphocholine + acetate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
german Holstein heifers | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| from endometrium and plasma | Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| endometrium | isozyme in endometrium is of the plasma enzyme type, enzyme activity decreases on day 20 in pregnant cows compared to cyclic cows on the same day, which show no changes in enzyme activity level | Bos taurus | - |
| plasma | plasma isozyme | Bos taurus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O | i.e. platelet-activation factor | Bos taurus | 1-alkyl-sn-glycero-3-phosphocholine + acetate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 45000, plasma and endometrial enzyme, SDS-PAGE | Bos taurus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PAF-acetylhydrolase | - |
Bos taurus |
| PAF-AH | - |
Bos taurus |
| platelet-activating factor acetylhydrolase | - |
Bos taurus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Bos taurus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
PBS, assay at | Bos taurus |
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Release 2023.1 (January 2023)
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