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Literature summary for 3.1.1.4 extracted from

  • Mouchlis, V.D.; Bucher, D.; McCammon, J.A.; Dennis, E.A.
    Membranes serve as allosteric activators of phospholipase A2, enabling it to extract, bind, and hydrolyze phospholipid substrates (2015), Proc. Natl. Acad. Sci. USA, 112, E516-E525 .
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
additional information membranes serve as allosteric activators of phospholipase A2, enabling it to extract, bind, and hydrolyze phospholipid substrates Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Homo sapiens 5829
-

Organism

Organism UniProt Comment Textmining
Homo sapiens O60733
-
-
Homo sapiens P47712
-
-

Synonyms

Synonyms Comment Organism
calcium-independent group VIA iPLA2
-
Homo sapiens
cytosolic group IVA cPLA2
-
Homo sapiens
iPLA2
-
Homo sapiens
PLA2
-
Homo sapiens
Pla2g4a
-
Homo sapiens
PLA2G6
-
Homo sapiens

General Information

General Information Comment Organism
metabolism the enzyme catalyzes the hydrolysis of phospholipid substrates that compose the membrane bilayers Homo sapiens