Inhibitors | Comment | Organism | Structure |
---|---|---|---|
25-O-acetyl-petrosaspongiolide M | an anti-inflammatory marine natural product | Homo sapiens | |
additional information | structural analysis of PLA2-inhibitor complexes, computational and mass spectrometry analysis, molecular dynamics simulations, overview | Homo sapiens | |
petrosaspongiolide M | an anti-inflammatory marine natural product, mechanism of sPLA2-IIA inactivation, overview | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | the secretory isozyme is Ca2+-dependent | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P14555 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | sPLA2-IIA activity assays using the fluorescent probe ADIFAB, which consists of an acrylodan derivative of rat intestinal fatty acid binding protein that exhibits a shift in fluorescence upon binding to long-chain native fatty acids | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Group IIA phospholipase A2 | - |
Homo sapiens |
group IIA secretory phospholipase A2 | - |
Homo sapiens |
sPLA2-IIA | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Homo sapiens |