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Literature summary for 3.1.1.4 extracted from

  • Antonopoulou, G.; Barbayianni, E.; Magrioti, V.; Cotton, N.; Stephens, D.; Constantinou-Kokotou, V.; Dennis, E.A.; Kokotos, G.
    Structure-activity relationships of natural and non-natural amino acid-based amide and 2-oxoamide inhibitors of human phospholipase A2 enzymes (2008), Bioorg. Med. Chem., 16, 10257-10269.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.1.4

Inhibitors

Inhibitors Comment Organism Structure
(R)-4-(7-phenylheptanamido)octanoic acid
-
 Homo sapiens
(R)-gamma-norleucine a highly selective inhibitor of isozyme GV sPLA2 Homo sapiens
(R)-methyl 6-methyl-4-(2-oxohexadecanamido)heptanoate
-
 Homo sapiens
(S)-ethyl 6-(2-oxohexadecanamido)decanoate
-
 Homo sapiens
(S)-methyl 4-(2-oxohexadecanamido)octanoate
-
 Homo sapiens
(S)-methyl 4-(7-phenylheptanamido)octanoate
-
 Homo sapiens
(S)-tert-butyl 4-(2-oxohexadecanamido)pentanoate
-
 Homo sapiens
(S,2E,4E)-6-(2-oxohexadecanamido)deca-2,4-dienoic acid
-
 Homo sapiens
(S,2E,4E)-ethyl 6-(2-oxohexadecanamido)deca-2,4-dienoate
-
 Homo sapiens
2-oxo-N-(4-oxooctyl)hexadecanamide
-
 Homo sapiens
allyl 4-(2-oxohexadecanamido)butanoate
-
 Homo sapiens
benzyl 4-(2-oxohexadecanamido)butanoate
-
 Homo sapiens
ethyl 2-(2-oxohexadecanamido)acetate
-
 Homo sapiens
ethyl 3-(2-oxohexadecanamido)propanoate
-
 Homo sapiens
ethyl 4-(2-oxohexadecanamido)benzoate
-
 Homo sapiens
ethyl 5-(2-oxohexadecanamido)pentanoate
-
 Homo sapiens
methyl 2-(2-oxo-8-phenyloctanamido)acetate
-
 Homo sapiens
methyl 2-(2-oxohexadecanamido)acetate
-
 Homo sapiens
methyl 2-(7-phenylheptanamido)acetate
-
 Homo sapiens
methyl 3-(2-oxohexadecanamido)propanoate
-
 Homo sapiens
methyl 5-(2-oxohexadecanamido)pentanoate
-
 Homo sapiens
additional information relative inhibition rates of isozymes GIVA cPLA2, GVIA iPLA2, GVsPLA2, with 2-oxoamide compounds, structure-activity relationships, overview Homo sapiens
N-(4-ethoxybutyl)-2-oxohexadecanamide
-
 Homo sapiens
tert-butyl 2-(2-oxohexadecanamido)acetate
-
 Homo sapiens
tert-butyl 3-(2-oxo-8-phenyloctanamido)propanoate
-
 Homo sapiens
tert-butyl 3-(2-oxohexadecanamido)propanoate
-
 Homo sapiens
tert-butyl 3-(7-phenylheptanamido)propanoate
-
 Homo sapiens
tert-butyl 5-(2-oxohexadecanamido)pentanoate
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular secretory phospholipase isozyme GV sPLA2 Homo sapiens
-
-
intracellular isozymes GIVA cPLA2 and GVIA iPLA2 Homo sapiens 5622
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
GIVA cPLA2
-
 Homo sapiens
GV sPLA2
-
 Homo sapiens
GVIA iPLA2
-
 Homo sapiens
secretory phospholipase
-
 Homo sapiens