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Literature summary for 3.1.1.4 extracted from

  • Stewart, A.; Ghosh, M.; Spencer, D.M.; Leslie, C.C.
    Enzymatic properties of human cytosolic phospholipase A2g (2002), J. Biol. Chem., 277, 29526-29536.
    View publication on PubMed
Search for more literature for 3.1.1.4

Cloned(Commentary)

Cloned (Comment) Organism
cPLA2gamma, expressed in Sf9 cells, lung fibroblasts and KEK293 cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
methyl arachidonyl fluorophosphonate 50% inhibition at 0.0005 mM Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-
membrane after expression in Sf9, lung fibroblasts and HEK293 cells Homo sapiens 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
61000
-
 SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens role in mediating fatty acid release from intact cells ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme has higher phospholipase activity than PLA2 activity, sequentially hydrolyzes fatty acid from the sn-2 and sn-1 positions of phosphatidylcholine Homo sapiens ?
-
 ?
additional information role in mediating fatty acid release from intact cells Homo sapiens ?
-
 ?