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Literature summary for 3.1.1.4 extracted from

  • Fuly, A.L.; de Miranda, A.L.; Zingali, R.B.; Guimaraes, J.A.
    Purification and characterization of a phospholipase A2 isoenzyme isolated from Lachesis muta snake venom (2002), Biochem. Pharmacol., 63, 1589-1597.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
4-bromophenacyl bromide abolishes inhibitory effect upon collagen- and ADP-induced platelet aggregation and the edematogenic effect Lachesis muta

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
18000
-
-
Lachesis muta

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Lachesis muta inhibits platelet aggregation induced by collagen and ADP ?
-
?

Organism

Organism UniProt Comment Textmining
Lachesis muta
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Lachesis muta

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
Lachesis muta
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Lachesis muta

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information inhibits platelet aggregation induced by collagen and ADP Lachesis muta ?
-
?

Synonyms

Synonyms Comment Organism
LM-PLA2-I
-
Lachesis muta
LM-PLA2-II
-
Lachesis muta

pI Value

Organism Comment pI Value Maximum pI Value
Lachesis muta isoform lm-PLA2-I, isoelectric focusing, pH gradient pH 2.5-6.5 and pH 3-10 4.8 4.7
Lachesis muta isoform lm-PLA2-II, isoelectric focusing, pH gradient pH 2.5-6.5 and pH 3-10
-
5.4