Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EGTA | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
90000 | - |
SDS-PAGE | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
phospholipids + H2O | Homo sapiens | release of arachidonic acid: biosynthesis of leucotrienes, thromboxans and prostaglandins | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
column chromatography steps, 11700fold | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
platelet | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.259 | - |
substrate: 1-acyl-2-arachidonoyl-glycerophosphocholine | Homo sapiens |
Storage Stability | Organism |
---|---|
-80°C | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-acyl-2-arachidonoyl-glycerophosphocholine + H2O | - |
Homo sapiens | 1-acyl-glycerophosphocholine + arachidonic acid | - |
? | |
1-acyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine + H2O | - |
Homo sapiens | 1-acyl-sn-glycero-3-phosphoethanolamine + arachidonic acid | - |
? | |
1-acyl-2-linoleoyl-3-phosphoethanolamine + H2O | - |
Homo sapiens | 1-acyl-3-phosphoethanolamine + linolic acid | - |
? | |
1-acyl-2-linoleoyl-glycerophosphocholine + H2O | - |
Homo sapiens | 1-acyl-glycerophosphocholine + linolic acid | - |
? | |
phospholipids + H2O | release of arachidonic acid: biosynthesis of leucotrienes, thromboxans and prostaglandins | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | - |
Homo sapiens |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
2 | - |
exposure to acidic conditions, i.e. pH 2 for 60 min at 4°C, causes irreversible loss of activity, stable in basic medium | Homo sapiens |