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Literature summary for 3.1.1.4 extracted from
- Purification and characterization of a phospholipase A2 from human ileal mucosa (1993), Biochim. Biophys. Acta, 1170, 125-130.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Homo sapiens |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 14000 | - |
heparin-sepharose affinity chromatography, SDS-PAGE after digestion with thrombin, SDS-PAGE | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phospholipids + H2O | Homo sapiens | eicosanoids | ? | - |
? | |
| phospholipids + H2O | Homo sapiens | inflammatory diseases | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| column chromatography, 4500fold | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cecum mucosa | - |
Homo sapiens | - |
| colonic mucosa | ascending, transverse, descending, sigmoid colon | Homo sapiens | - |
| ileal mucosa | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0062 | - |
sigmoid colon mucosa, substrate: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol | Homo sapiens |
| 0.0071 | - |
cecal mucosa, substrate: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol | Homo sapiens |
| 0.0072 | - |
ascending colon mucosa, substrate: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol | Homo sapiens |
| 0.0078 | - |
transverse colon mucosa, substrate: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol | Homo sapiens |
| 0.0092 | - |
descending colon mucosa, substrate: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol | Homo sapiens |
| 0.0509 | - |
ileal mucosa, substrate: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol | Homo sapiens |
| 306 | - |
purified PLA2 from ileal mucosa, substrate: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine + H2O | - |
Homo sapiens | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol + H2O | - |
? | |
| 1-palmitoyl-2-oleoylphosphatidylcholine + H2O | - |
Homo sapiens | 1-palmitoyl-glycerophosphocholine + oleic acid | - |
? | |
| phospholipids + H2O | eicosanoids | Homo sapiens | ? | - |
? | |
| phospholipids + H2O | inflammatory diseases | Homo sapiens | ? | - |
? | |
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