BRENDA - Enzyme Database
show all sequences of 3.1.1.39

Actinomycin lactonase

Perlman, D.; Methods Enzymol. 43, 763-767 (1975)

Data extracted from this reference:

KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.0114
-
actinomycin
-
Actinoplanes missouriensis
Organism
Organism
UniProt
Commentary
Textmining
Actinoplanes missouriensis
-
-
-
Purification (Commentary)
Purification (Commentary)
Organism
-
Actinoplanes missouriensis
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
additional information
-
0.5 mg product formed per 60 min per mg of protein
Actinoplanes missouriensis
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
actinomycin + H2O
-
80926
Actinoplanes missouriensis
actinomycinic monolactone
-
80926
Actinoplanes missouriensis
?
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
38
-
-
Actinoplanes missouriensis
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.8
-
-
Actinoplanes missouriensis
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.0114
-
actinomycin
-
Actinoplanes missouriensis
Purification (Commentary) (protein specific)
Commentary
Organism
-
Actinoplanes missouriensis
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
additional information
-
0.5 mg product formed per 60 min per mg of protein
Actinoplanes missouriensis
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
actinomycin + H2O
-
80926
Actinoplanes missouriensis
actinomycinic monolactone
-
80926
Actinoplanes missouriensis
?
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
38
-
-
Actinoplanes missouriensis
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.8
-
-
Actinoplanes missouriensis
Other publictions for EC 3.1.1.39
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
80928
Mehta
-
Actinomycin D inactivating enz ...
Actinoplanes missouriensis, Dactylosporangium aurantiacum, Dactylosporangium thailandense, Streptomyces purpureus, Planobispora longispora, Planobispora rosea, Spirillospora albida, Spirillospora sp., Kutzneria albida, Streptosporangium brasiliense, Streptosporangium roseum, Streptosporangium violaceochromogenes, Kutzneria viridogrisea
Eur. J. Appl. Microbiol. Biotechnol.
5
165-170
1978
-
-
-
-
-
-
-
-
1
-
-
-
-
13
-
-
-
-
-
-
-
-
13
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
13
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
80926
Perlman
Actinomycin lactonase ...
Actinoplanes missouriensis
Methods Enzymol.
43
763-767
1975
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
1
-
1
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
-
-
1
-
1
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
80927
Hou
Microbial transformations of p ...
Actinoplanes missouriensis
J. Biol. Chem.
245
1289-1295
1970
-
-
-
-
-
-
5
1
-
-
1
1
-
5
-
-
1
-
-
-
-
1
2
-
-
2
1
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
1
-
-
1
1
-
-
-
1
-
-
-
1
2
-
2
1
-
-
1
1
-
-
-
-
-
-
-
-