BRENDA - Enzyme Database
show all sequences of 3.1.1.37

Preparation and properties of a steroid lactonase

Holmlund, C.E.; Blank, R.H.; Arch. Biochem. Biophys. 109, 29-35 (1965)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
HgCl2
-
Acremonium chrysogenum
p-chloromercuriphenylsulfonate
-
Acremonium chrysogenum
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Mg2+
optimum: 0.1 M, enhances
Acremonium chrysogenum
Mn2+
optimum: 0.1 M, enhances
Acremonium chrysogenum
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
testololactone + H2O
Acremonium chrysogenum
-
?
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Acremonium chrysogenum
-
-
-
Purification (Commentary)
Purification (Commentary)
Organism
-
Acremonium chrysogenum
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
16alpha-hydroxytestololactone + H2O
50% the rate of testololactone
80923
Acremonium chrysogenum
16alpha-hydroxytestolate
-
80923
Acremonium chrysogenum
?
additional information
not: steroids containing gamma-lactones, digitoxigenin, spirolactone
80923
Acremonium chrysogenum
?
-
-
-
?
testolate
lactone formation more rapidly than lactone hydrolysis, only at pH 6, presence of Mn2+
80923
Acremonium chrysogenum
testololactone + H2O
-
80923
Acremonium chrysogenum
r
testololactone + H2O
-
80923
Acremonium chrysogenum
testolate
-
80923
Acremonium chrysogenum
r
testololactone + H2O
-
80923
Acremonium chrysogenum
?
-
-
-
?
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
HgCl2
-
Acremonium chrysogenum
p-chloromercuriphenylsulfonate
-
Acremonium chrysogenum
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Mg2+
optimum: 0.1 M, enhances
Acremonium chrysogenum
Mn2+
optimum: 0.1 M, enhances
Acremonium chrysogenum
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
testololactone + H2O
Acremonium chrysogenum
-
?
-
-
?
Purification (Commentary) (protein specific)
Commentary
Organism
-
Acremonium chrysogenum
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
16alpha-hydroxytestololactone + H2O
50% the rate of testololactone
80923
Acremonium chrysogenum
16alpha-hydroxytestolate
-
80923
Acremonium chrysogenum
?
additional information
not: steroids containing gamma-lactones, digitoxigenin, spirolactone
80923
Acremonium chrysogenum
?
-
-
-
?
testolate
lactone formation more rapidly than lactone hydrolysis, only at pH 6, presence of Mn2+
80923
Acremonium chrysogenum
testololactone + H2O
-
80923
Acremonium chrysogenum
r
testololactone + H2O
-
80923
Acremonium chrysogenum
testolate
-
80923
Acremonium chrysogenum
r
testololactone + H2O
-
80923
Acremonium chrysogenum
?
-
-
-
?
Other publictions for EC 3.1.1.37
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
80923
Holmlund
Preparation and properties of ...
Acremonium chrysogenum
Arch. Biochem. Biophys.
109
29-35
1965
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