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Literature summary for 3.1.1.34 extracted from
- Isolation, molecular properties, and kinetic characterization of lipoprotein lipase from rat heart (1977), J. Biol. Chem., 252, 4202-4209.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| apolipoprotein C-II | required | Rattus norvegicus | |
| heparin | increases hydrolytic activity | Rattus norvegicus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| apolipoprotein C I | - |
Rattus norvegicus | |
| apolipoprotein C III | - |
Rattus norvegicus | |
| diisopropyl fluorophosphate | - |
Rattus norvegicus | |
| NaCl | 0.5 M, 80% inhibition, 1 M, 90% inhibition | Rattus norvegicus | |
| phenylmethylsulfonyl fluoride | - |
Rattus norvegicus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 34000 | - |
x * 34000, SDS-PAGE, equilibrium sedimentation in presence of 6 M guanidine HCl and 0.1% mercaptoethanol | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| side-chain modification | glycoprotein | Rattus norvegicus |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 10.77 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | no absolute specificity for monolayers of triglycerides, hydrolysis of diglyceride monolayers at comparable rates | Rattus norvegicus | ? | - |
? | |
| trioctanoin + H2O | - |
Rattus norvegicus | ? | - |
? | |
| triolein + H2O | - |
Rattus norvegicus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 34000, SDS-PAGE, equilibrium sedimentation in presence of 6 M guanidine HCl and 0.1% mercaptoethanol | Rattus norvegicus |
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