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Literature summary for 3.1.1.34 extracted from

  • Unal, R.; Pokrovskaya, I.; Tripathi, P.; Monia, B.P.; Kern, P.A.; Ranganathan, G.
    Translational regulation of lipoprotein lipase in adipocytes: depletion of cellular protein kinase Calpha activates binding of the C subunit of protein kinase A to the 3-untranslated region of the lipoprotein lipase mRNA (2008), Biochem. J., 413, 315-322.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
additional information protein kinase Calpha depletion inhibits LPL translation through protein kinase A activation, LPL translational inhibition occurs through an RNA-binding complex involving protein kinase A subunits and A-kinase-anchoring protein 121, LPL is also translationally repressed following depletion of cellular protein kinase C either through prolonged treatment with phorbol esters or through the use of antisense oligonucleotides to protein kinase Calpha Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
3T3-F442A cell
-
Mus musculus
-
adipocyte
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
triolein + H2O
-
Mus musculus oleate + diolein
-
?

Synonyms

Synonyms Comment Organism
LPL
-
Mus musculus