Literature summary for 3.1.1.34 extracted from

Kota, R.S.; Ramana, C.V.; Tenorio, F.A.; Enelow, R.I.; Rutledge, J.C.
Differential effects of lipoprotein lipase on tumor necrosis factor-alpha and interferon-gamma-mediated gene expression in human endothelial cells (2005), J. Biol. Chem., 280, 31076-31084.

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Application

Application	Comment	Organism
medicine	enzyme significantly suppresses TNF-alpha-induced gene expression, and this suppression is reversed by tetrahydrolipstatin and heparinase. In contrast, enzyme synergistically enhances IFN-gamma-induced gene expression	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
aorta	aortic endothelial cells	Homo sapiens	-
endothelium	aortic endothelial cells	Homo sapiens	-

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Release 2023.1 (January 2023)