Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Triton X-100 | 1%, 12.4fold increase in activity | Trypanosoma cruzi |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
chlorpromazine | 1 mM, 50% inhibition | Trypanosoma cruzi |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Trypanosoma cruzi | 5764 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
38000 | - |
1 * 38000, SDS-PAGE | Trypanosoma cruzi |
40000 | - |
gel filtration | Trypanosoma cruzi |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-palmitoyl-2-oleoyl-phosphatidylcholine + H2O | Trypanosoma cruzi | - |
2-oleoyl-lysophosphatidylcholine + palmitic acid | - |
? | |
phosphatidylcholine + H2O | Trypanosoma cruzi | - |
2-acylglycerophosphocholine + a carboxylate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma cruzi | - |
Plase A1 may play a role in the pathogenesis of Chagas' disease | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | indicated by binding to ConA-Sepharose | Trypanosoma cruzi |
Purification (Comment) | Organism |
---|---|
purified from epimastogote homogenate supernatants, DEAE-Trisacryl, ConA-Sepharose 4B, CM-Sepharose | Trypanosoma cruzi |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.35 | - |
- |
Trypanosoma cruzi |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-palmitoyl-2-oleoyl-phosphatidylcholine + H2O | - |
Trypanosoma cruzi | 2-oleoyl-lysophosphatidylcholine + palmitic acid | - |
? | |
phosphatidylcholine + H2O | - |
Trypanosoma cruzi | 2-acylglycerophosphocholine + a carboxylate | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 38000, SDS-PAGE | Trypanosoma cruzi |
Synonyms | Comment | Organism |
---|---|---|
Plase A1 | - |
Trypanosoma cruzi |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
4 | 5 | - |
Trypanosoma cruzi |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
3 | 7 | approx. 50% of maximal activity at pH 3.0, approx. 20% of maximal activity at pH 6.0 | Trypanosoma cruzi |