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Literature summary for 3.1.1.3 extracted from

  • Eichmann, T.O.; Kumari, M.; Haas, J.T.; Farese, R.V.; Zimmermann, R.; Lass, A.; Zechner, R.
    Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases (2012), J. Biol. Chem., 287, 41446-41457.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
CGI-58 co-activator Mus musculus

Cloned(Commentary)

Cloned (Comment) Organism
expressed in in Cos-7 cells Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus the enzyme hydrolyzes long-chain fatty acid esters in vivo with a modest substrate preference for C16:1 ?
-
?
additional information Mus musculus C57BL/6 the enzyme hydrolyzes long-chain fatty acid esters in vivo with a modest substrate preference for C16:1 ?
-
?
triacylglycerol + H2O Mus musculus
-
diacylglycerol + a carboxylate the enzyme specifically generates sn-1,3 and, in the presence of its co-activator CGI-58, sn-1,3 and sn-2,3 diacylglycerol ?
triacylglycerol + H2O Mus musculus C57BL/6
-
diacylglycerol + a carboxylate the enzyme specifically generates sn-1,3 and, in the presence of its co-activator CGI-58, sn-1,3 and sn-2,3 diacylglycerol ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme hydrolyzes long-chain fatty acid esters in vivo with a modest substrate preference for C16:1 Mus musculus ?
-
?
additional information the enzyme hydrolyzes long-chain fatty acid esters in vivo with a modest substrate preference for C16:1 Mus musculus C57BL/6 ?
-
?
triacylglycerol + H2O
-
Mus musculus diacylglycerol + a carboxylate the enzyme specifically generates sn-1,3 and, in the presence of its co-activator CGI-58, sn-1,3 and sn-2,3 diacylglycerol ?
triacylglycerol + H2O
-
Mus musculus C57BL/6 diacylglycerol + a carboxylate the enzyme specifically generates sn-1,3 and, in the presence of its co-activator CGI-58, sn-1,3 and sn-2,3 diacylglycerol ?
trilinolein + H2O lowest activity Mus musculus ?
-
?
trilinolein + H2O lowest activity Mus musculus C57BL/6 ?
-
?
trilinolenin + H2O
-
Mus musculus ?
-
?
trilinolenin + H2O
-
Mus musculus C57BL/6 ?
-
?
triolein + H2O
-
Mus musculus ?
-
?
triolein + H2O
-
Mus musculus C57BL/6 ?
-
?
tripalmitolein + H2O highest activity Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
adipose triglyceride lipase
-
Mus musculus
ATGL
-
Mus musculus