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Literature summary for 3.1.1.3 extracted from

  • Patel, R.N.; Banerjee, A.; Ko, R.Y.; Howell, J.M.; Li, W.S.; Comezoglu, F.T.
    Enzymic preparation of (3R-cis)-3-acetyloxy-4-phenyl-2-azetidinone: a taxol side-chain synthon (1994), Biotechnol. Appl. Biochem., 20, 23-33.
No PubMed abstract available
Search for more literature for 3.1.1.3

Application

Application Comment Organism
synthesis production of (3R,4S)-cis-azetidinone acetate, which is an intermediate for the synthesis of paclitaxel Burkholderia cepacia

Organism

Organism UniProt Comment Textmining
Burkholderia cepacia
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cis-3-(acetyloxy)-4-phenyl-2-azetidinone + H2O
-
 Burkholderia cepacia (3R,4S)-cis-3-(acetyloxy)-4-phenyl-2-azetidinone + (3S,4R)-cis-3-hydroxy-4-phenyl-2-azetidinone + acetate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
29
-
-
 Burkholderia cepacia

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
 Burkholderia cepacia