Protein Variants | Comment | Organism |
---|---|---|
additional information | excess of charged tRNALys maintains low levels of peptidyl-tRNA hydrolase in pth mutants at a non-permissive temperature, strain AA7852 phenotype and levels of aminoacyl- and peptidyl-tRNAs, overproduction of tRNALys suppresses the effects of pthTs mutation at 41°C but not at 43°C, and increases the levels of aminoacyl-tRNA, overview | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
peptidyl-tRNALys + H2O | Escherichia coli | accumulation of peptidyl-tRNA due to enzyme misfunction is toxic to the cells, overproduction of tRNALys suppresses the effects of pthTs mutation at 41°C but not at 43°C, and increases the levels of aminoacyl-tRNA | peptide + tRNALys | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
mutant strain AA7852 with temperature-sensitive Pth, gene pthTs | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | mutant strain AA7852 with temperature-sensitive Pth grown at 32°C and at 41°C | Escherichia coli | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
peptidyl-tRNALys + H2O | - |
Escherichia coli | peptide + tRNALys | - |
? | |
peptidyl-tRNALys + H2O | accumulation of peptidyl-tRNA due to enzyme misfunction is toxic to the cells, overproduction of tRNALys suppresses the effects of pthTs mutation at 41°C but not at 43°C, and increases the levels of aminoacyl-tRNA | Escherichia coli | peptide + tRNALys | - |
? |
Synonyms | Comment | Organism |
---|---|---|
peptidyl-tRNA hydrolase | - |
Escherichia coli |
PTH | - |
Escherichia coli |