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Literature summary for 3.1.1.25 extracted from
- Effect of certain non-steroidal anti-inflammatory drugs on the paraoxonase 2 (PON2) in human monocytic cell line U937 (2018), Arch. Physiol. Biochem., 124, 378-382 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| diclofenac sodium | diclofenac sodium in 0.845 mM dose during 6-12 h of incubation results in a significant decline in the lactonase activity | Homo sapiens |  |
| tenoxicam | tenoxicam in 0.74mM dose during 6 h of incubation results in a significant decline in the lactonase activity | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| monocyte | - |
Homo sapiens | - |
| U-937 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dihydrocoumarin + H2O | - |
Homo sapiens | 3-(2-hydroxyphenyl)-propionic acid | - |
? | |
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Release 2023.1 (January 2023)
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