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Literature summary for 3.1.1.25 extracted from

  • Bzdrenga, J.; Hiblot, J.; Gotthard, G.; Champion, C.; Elias, M.; Chabriere, E.
    SacPox from the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius is a proficient lactonase (2014), BMC Res. Notes, 7, 333.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.1.25

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.109
-
 nonanoic-1,4-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
0.168
-
 undecanoic-1,5-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
0.178
-
 N-(2-oxotetrahydrofuran-3-yl)pentanamide pH 8.3, 25°C Sulfolobus acidocaldarius
0.185
-
 dodecanoic-1,5-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
0.213
-
 9-oxo-N-(2-oxotetrahydrofuran-3-yl)undecanamide pH 8.3, 25°C Sulfolobus acidocaldarius
0.242
-
 dodecanoic-1,4-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
0.348
-
 nonanoic-1,5-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
0.388
-
 gamma-heptanolide pH 8.3, 25°C Sulfolobus acidocaldarius
0.578
-
 undecanoic-1,4-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
0.836
-
 7-oxo-N-(2-oxotetrahydrofuran-3-yl)nonanamide pH 8.3, 25°C Sulfolobus acidocaldarius
1.031
-
 epsilon-caprolactone pH 8.3, 25°C Sulfolobus acidocaldarius

Organism

Organism UniProt Comment Textmining
Sulfolobus acidocaldarius Q4J6Z8
-
-
Sulfolobus acidocaldarius DSM 639 Q4J6Z8
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7-oxo-N-(2-oxotetrahydrofuran-3-yl)nonanamide + H2O
-
 Sulfolobus acidocaldarius 3-hydroxy-2-[(7-oxononanoyl)amino]propanoic acid
-
 ?
7-oxo-N-(2-oxotetrahydrofuran-3-yl)nonanamide + H2O
-
 Sulfolobus acidocaldarius DSM 639 3-hydroxy-2-[(7-oxononanoyl)amino]propanoic acid
-
 ?
9-oxo-N-(2-oxotetrahydrofuran-3-yl)undecanamide + H2O
-
 Sulfolobus acidocaldarius 3-hydroxy-2-[(9-oxoundecanoyl)amino]propanoic acid
-
 ?
dodecanoic-1,4-lactone + H2O
-
 Sulfolobus acidocaldarius 4-hydroxydodecanoate
-
 ?
dodecanoic-1,5-lactone + H2O
-
 Sulfolobus acidocaldarius 5-hydroxydodecanoate
-
 ?
epsilon-caprolactone + H2O
-
 Sulfolobus acidocaldarius 6-hydroxyhexanoate
-
 ?
epsilon-caprolactone + H2O
-
 Sulfolobus acidocaldarius DSM 639 6-hydroxyhexanoate
-
 ?
gamma-heptanolide + H2O
-
 Sulfolobus acidocaldarius 4-hydroxyheptanoate
-
 ?
N-(2-oxotetrahydrofuran-3-yl)pentanamide + H2O
-
 Sulfolobus acidocaldarius 3-hydroxy-2-(pentanoylamino)propanoic acid
-
 ?
nonanoic-1,4-lactone + H2O
-
 Sulfolobus acidocaldarius 4-hydroxynonanoate
-
 ?
nonanoic-1,5-lactone + H2O
-
 Sulfolobus acidocaldarius 5-hydroxynonanoate
-
 ?
undecanoic-1,4-lactone + H2O
-
 Sulfolobus acidocaldarius 4-hydroxyundecanoate
-
 ?
undecanoic-1,5-lactone + H2O
-
 Sulfolobus acidocaldarius 5-hydroxyundecanoate
-
 ?

Synonyms

Synonyms Comment Organism
Saci_2140 locus name Sulfolobus acidocaldarius
SacPox
-
 Sulfolobus acidocaldarius

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Sulfolobus acidocaldarius

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.34
-
 undecanoic-1,4-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
0.53
-
 dodecanoic-1,4-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
0.89
-
 7-oxo-N-(2-oxotetrahydrofuran-3-yl)nonanamide pH 8.3, 25°C Sulfolobus acidocaldarius
0.94
-
 N-(2-oxotetrahydrofuran-3-yl)pentanamide pH 8.3, 25°C Sulfolobus acidocaldarius
1.03
-
 9-oxo-N-(2-oxotetrahydrofuran-3-yl)undecanamide pH 8.3, 25°C Sulfolobus acidocaldarius
1.05
-
 undecanoic-1,5-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
2.64
-
 nonanoic-1,4-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
3.34
-
 dodecanoic-1,5-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
4.55
-
 nonanoic-1,5-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
10.25
-
 gamma-heptanolide pH 8.3, 25°C Sulfolobus acidocaldarius
15.04
-
 epsilon-caprolactone pH 8.3, 25°C Sulfolobus acidocaldarius

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.3
-
 assay at Sulfolobus acidocaldarius

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
0.59
-
 undecanoic-1,4-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
1.07
-
 7-oxo-N-(2-oxotetrahydrofuran-3-yl)nonanamide pH 8.3, 25°C Sulfolobus acidocaldarius
2.21
-
 dodecanoic-1,4-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
4.88
-
 9-oxo-N-(2-oxotetrahydrofuran-3-yl)undecanamide pH 8.3, 25°C Sulfolobus acidocaldarius
5.28
-
 N-(2-oxotetrahydrofuran-3-yl)pentanamide pH 8.3, 25°C Sulfolobus acidocaldarius
6.22
-
 undecanoic-1,5-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
13.1
-
 nonanoic-1,5-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
14.6
-
 epsilon-caprolactone pH 8.3, 25°C Sulfolobus acidocaldarius
18.1
-
 dodecanoic-1,5-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
24.4
-
 nonanoic-1,4-lactone pH 8.3, 25°C Sulfolobus acidocaldarius
26.4
-
 gamma-heptanolide pH 8.3, 25°C Sulfolobus acidocaldarius