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Literature summary for 3.1.1.23 extracted from

  • Heier, C.; Taschler, U.; Rengachari, S.; Oberer, M.; Wolinski, H.; Natter, K.; Kohlwein, S.D.; Leber, R.; Zimmermann, R.
    Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomyces cerevisiae (2010), Biochim. Biophys. Acta, 1801, 1063-1071.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
lipid droplet
-
 Saccharomyces cerevisiae 5811
-
membrane
-
 Saccharomyces cerevisiae 16020
-

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

Purification (Comment) Organism
HisTrap column chromatography, gel filtration Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-monooleoylglycerol + H2O
-
 Saccharomyces cerevisiae oleic acid + glycerol
-
 ?
rac-1(3)-oleoylglycerol + H2O
-
 Saccharomyces cerevisiae oleate + glycerol
-
 ?

Synonyms

Synonyms Comment Organism
MAG hydrolase
-
 Saccharomyces cerevisiae
MGH
-
 Saccharomyces cerevisiae
MGL
-
 Saccharomyces cerevisiae
monoacylglycerol hydrolase
-
 Saccharomyces cerevisiae
monoglyceride lipase
-
 Saccharomyces cerevisiae
Yju3p
-
 Saccharomyces cerevisiae

General Information

General Information Comment Organism
malfunction Yju3p deficiency causes monoacylglycerol accumulation in vitro Saccharomyces cerevisiae
physiological function Yju3p is required for efficient degradation of monoacylglycerol in yeast Saccharomyces cerevisiae