Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | high fat feeding induces the enzyme in the intestine, but starvation does not have an effect on the enzyme activity | Mus musculus |
Cloned (Comment) | Organism |
---|---|
quantitative RT-PCR for analysis of intestinal MGL mRNA expression | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | developmental and nutritional regulation of the enzyme in the intestine, overview | ? | - |
? | |
additional information | Mus musculus | tissue-specific developmental and nutritional regulation of the enzyme, post-transcriptional regulation of expression occurs in the intestine, while transcriptional regulation is the primary mechanism for hepatic MGL expression, overview | ? | - |
? | |
additional information | Mus musculus C57BL/6 | tissue-specific developmental and nutritional regulation of the enzyme, post-transcriptional regulation of expression occurs in the intestine, while transcriptional regulation is the primary mechanism for hepatic MGL expression, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
C57BL/6 mice | - |
Mus musculus C57BL/6 | - |
C57BL/6 mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipose tissue | - |
Mus musculus | - |
Caco-2 cell | - |
Homo sapiens | - |
enterocyte | - |
Homo sapiens | - |
intestine | - |
Homo sapiens | - |
liver | liver MGL mRNA, protein and activity all increased 5-10-fold during development | Mus musculus | - |
small intestine | mucosa, post-transcriptional regulation of expression, the enzyme expression is also developmentally regulated, quantitative RT-PCR analysis, overview | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | developmental and nutritional regulation of the enzyme in the intestine, overview | Homo sapiens | ? | - |
? | |
additional information | tissue-specific developmental and nutritional regulation of the enzyme, post-transcriptional regulation of expression occurs in the intestine, while transcriptional regulation is the primary mechanism for hepatic MGL expression, overview | Mus musculus | ? | - |
? | |
additional information | tissue-specific developmental and nutritional regulation of the enzyme, post-transcriptional regulation of expression occurs in the intestine, while transcriptional regulation is the primary mechanism for hepatic MGL expression, overview | Mus musculus C57BL/6 | ? | - |
? | |
sn-2-monoolein + H2O | - |
Mus musculus | glycerol + oleic acid | - |
? | |
sn-2-monoolein + H2O | - |
Homo sapiens | glycerol + oleic acid | - |
? | |
sn-2-monoolein + H2O | - |
Mus musculus C57BL/6 | glycerol + oleic acid | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MGL | - |
Mus musculus |
MGL | - |
Homo sapiens |
monoacylglycerol lipase | - |
Mus musculus |
monoacylglycerol lipase | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
23 | - |
assay at | Mus musculus |
23 | - |
assay at | Homo sapiens |