Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.1.23 extracted from

  • Chon, S.H.; Zhou, Y.X.; Dixon, J.L.; Storch, J.
    Intestinal monoacylglycerol metabolism: developmental and nutritional regulation of monoacylglycerol lipase and monoacylglycerol acyltransferase (2007), J. Biol. Chem., 282, 33346-33357.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information high fat feeding induces the enzyme in the intestine, but starvation does not have an effect on the enzyme activity Mus musculus

Cloned(Commentary)

Cloned (Comment) Organism
quantitative RT-PCR for analysis of intestinal MGL mRNA expression Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens developmental and nutritional regulation of the enzyme in the intestine, overview ?
-
?
additional information Mus musculus tissue-specific developmental and nutritional regulation of the enzyme, post-transcriptional regulation of expression occurs in the intestine, while transcriptional regulation is the primary mechanism for hepatic MGL expression, overview ?
-
?
additional information Mus musculus C57BL/6 tissue-specific developmental and nutritional regulation of the enzyme, post-transcriptional regulation of expression occurs in the intestine, while transcriptional regulation is the primary mechanism for hepatic MGL expression, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
C57BL/6 mice
-
Mus musculus C57BL/6
-
C57BL/6 mice
-

Source Tissue

Source Tissue Comment Organism Textmining
adipose tissue
-
Mus musculus
-
Caco-2 cell
-
Homo sapiens
-
enterocyte
-
Homo sapiens
-
intestine
-
Homo sapiens
-
liver liver MGL mRNA, protein and activity all increased 5-10-fold during development Mus musculus
-
small intestine mucosa, post-transcriptional regulation of expression, the enzyme expression is also developmentally regulated, quantitative RT-PCR analysis, overview Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information developmental and nutritional regulation of the enzyme in the intestine, overview Homo sapiens ?
-
?
additional information tissue-specific developmental and nutritional regulation of the enzyme, post-transcriptional regulation of expression occurs in the intestine, while transcriptional regulation is the primary mechanism for hepatic MGL expression, overview Mus musculus ?
-
?
additional information tissue-specific developmental and nutritional regulation of the enzyme, post-transcriptional regulation of expression occurs in the intestine, while transcriptional regulation is the primary mechanism for hepatic MGL expression, overview Mus musculus C57BL/6 ?
-
?
sn-2-monoolein + H2O
-
Mus musculus glycerol + oleic acid
-
?
sn-2-monoolein + H2O
-
Homo sapiens glycerol + oleic acid
-
?
sn-2-monoolein + H2O
-
Mus musculus C57BL/6 glycerol + oleic acid
-
?

Synonyms

Synonyms Comment Organism
MGL
-
Mus musculus
MGL
-
Homo sapiens
monoacylglycerol lipase
-
Mus musculus
monoacylglycerol lipase
-
Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
23
-
assay at Mus musculus
23
-
assay at Homo sapiens