Any feedback?
Literature summary for 3.1.1.23 extracted from
- Purification and properties of a phospholipase A2/lipase preferring phosphatidic acid, bis(monoacylglycerol) phosphate, and monoacylglycerol from rat testis (2002), J. Biol. Chem., 277, 43674-43681.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| (4-amidinophenyl) methanesulfonyl fluoride | i.e. APMSF, inhibits at 0.5 mM | Rattus norvegicus |  |
| methyl arachidonyl fluorophosphonate | i.e. MAFP, inhibits at 0.05 mM | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| testis | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 8.21 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| bis(monoacylclycerol) phosphate + H2O | at pH 5.5 | Rattus norvegicus | ? | - |
? | |
| lysobisphosphatidic acid + H2O | at pH 5.5 | Rattus norvegicus | ? | - |
? | |
| monoarachidonoylglycerol + H2O | - |
Rattus norvegicus | arachidonic acid + glycerol | - |
? | |
| monolinoleoylglycerol + H2O | - |
Rattus norvegicus | linoic acid + glycerol | - |
? | |
| monooleoylglycerol + H2O | - |
Rattus norvegicus | oleic acid + glycerol | - |
? | |
| monostearoylglycerol + H2O | - |
Rattus norvegicus | stearic acid + glycerol | - |
? | |
| additional information | enzyme exhibits both phosphatidic acid-preferring phospholipase A2 and monoacylglycerol lipase activities with a modest specificity towards unsaturated acyl chains, veryl low di- and triaclyglycerol lipase activity | Rattus norvegicus | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | - |
phospholipase A2 activity | Rattus norvegicus |
| 8 | - |
lipase activity | Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
