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Literature summary for 3.1.1.2 extracted from
- Crystalline silica Min-U-Sil 5 induces oxidative stress in human bronchial epithelial cells BEAS-2B by reducing the efficiency of antiglycation and antioxidant enzymatic defenses (2009), Chem. Biol. Interact., 182, 13-21.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| methylglyoxal | decreases specific activity in a concentration-dependent manner | Homo sapiens |  |
| additional information | crystalline particles Min-U-Sil 5 reduce activity due to decreased protein concentrations | Homo sapiens |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | is required for catalysis | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| BEAS-2B cell | - |
Homo sapiens | - |
| bronchial epithelial cell | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0636 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrophenyl acetate + H2O | - |
Homo sapiens | 4-nitrophenol + acetate | - |
? | |
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