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Literature summary for 3.1.1.2 extracted from

  • Camuzcuoglu, H.; Arioz, D.T.; Toy, H.; Kurt, S.; Celik, H.; Erel, O.
    Serum paraoxonase and arylesterase activities in patients with epithelial ovarian cancer (2009), Gynecol. Oncol., 112, 481-485.
    View publication on PubMed
Search for more literature for 3.1.1.2

Application

Application Comment Organism
medicine diminished paraoxonase and arylesterase activity is associated with particular stage, grade and CA-125 level of ovarian cancer Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens PON1 plays a key role in the protection of low density lipoproteins and high density lipoproteins from oxidation by hydrolyzing activated phospholipids and lipid peroxide products ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P27169
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver the enzyme is synthesized in the liver Homo sapiens
-
serum the enzyme is secreted into the serum Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PON1 plays a key role in the protection of low density lipoproteins and high density lipoproteins from oxidation by hydrolyzing activated phospholipids and lipid peroxide products Homo sapiens ?
-
 ?
additional information PON1 is an high density lipoprotein-associated enzyme with three activities: paraoxonase, arylesterase and dyazoxonase Homo sapiens ?
-
 ?
phenyl acetate + H2O
-
 Homo sapiens phenol + acetate
-
 ?

Synonyms

Synonyms Comment Organism
arylesterase
-
 Homo sapiens