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Literature summary for 3.1.1.2 extracted from

  • Tavori, H.; Khatib, S.; Aviram, M.; Vaya, J.
    Characterization of the PON1 active site using modeling simulation, in relation to PON1 lactonase activity (2008), Bioorg. Med. Chem., 16, 7504-7509.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P27169
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-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PON1 hydrolyzes organophosphates, arylesters and lactones, whereas the lactones activity is assumed as the physio/pathological one Homo sapiens ?
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?
phenyl acetate + H2O shows highest hydrolytic rate towards phenyl acetate Homo sapiens phenol + acetate
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?