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Literature summary for 3.1.1.2 extracted from
- Continuous monitoring of arylesterase in human serum (2001), Clin. Chim. Acta, 308, 69-78.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-chloromercuribenzoate | complete inhibition at 0.2 mM | Homo sapiens |  |
| lanthanum(III) chloride | about 50% inhibition at 0.05 mM | Homo sapiens | |
| additional information | no inhibition by diisopropyl fluorophosphate and sodium fluoride | Homo sapiens | |
| N-ethylmaleimide | leads to 24fold reduced enzyme activity at 0.2 mM | Homo sapiens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | kinetics | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | serum | Homo sapiens | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| serum | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
assay developemnt | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-carboxythiophenyl acetate + H2O | - |
Homo sapiens | 2-carboxythiophenol + acetate | - |
? | |
| 2-methoxythiophenyl acetate + H2O | - |
Homo sapiens | 2-methoxythiophenol + acetate | - |
? | |
| 4-carboxyphenyl acetate + H2O | - |
Homo sapiens | 4-carboxyphenol + acetate | - |
? | |
| phenyl acetate + H2O | - |
Homo sapiens | phenol + acetate | - |
? | |
| S-(4-carboxyphenyl)-thioacetate + H2O | - |
Homo sapiens | 4-carboxythiophenol + acetate | - |
? | |
| thiophenyl acetate + H2O | - |
Homo sapiens | thiophenol + acetate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| More | also EC 3.1.8.1 | Homo sapiens |
| paraoxonase | - |
Homo sapiens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.8 | 8 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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