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Literature summary for 3.1.1.17 extracted from

  • Kondo, Y.; Inai, Y.; Sato, Y.; Handa, S.; Kubo, S.; Shimokado, K.; Goto, S.; Nishikimi, M.; Murayama, N.; Ishigami, A.
    Senecence marker protein 30 functions as gluconolactonase in L-ascorbic acid biosynthesis, and its knockout mice are prone to scurvy (2006), Proc. Natl. Acad. Sci. USA, 103, 5723-2728.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.1.17

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
9.4
-
 D-glucono-1,5-lactone pH 6.4 Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ 27% of the activation observed with Zn2+ Rattus norvegicus
Zn2+ required Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus senescence marker protein 30 plays a role in ascorbic acid biosynthesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-galactono-1,5-lactone + H2O
-
 Rattus norvegicus D-galactonate
-
 ?
D-glucono-1,5-lactone + H2O
-
 Rattus norvegicus D-gluconate
-
 ?
D-gulono-1,5-lactone + H2O
-
 Rattus norvegicus D-gulonate
-
 ?
L-galactono-1,5-lactone + H2O
-
 Rattus norvegicus L-galactonate
-
 ?
L-glucono-1,5-lactone + H2O
-
 Rattus norvegicus L-gluconate
-
 ?
L-gulono-1,5-lactone + H2O
-
 Rattus norvegicus L-gulonate
-
 ?
additional information senescence marker protein 30 plays a role in ascorbic acid biosynthesis Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
senescence marker protein 30
-
 Rattus norvegicus
SMP30
-
 Rattus norvegicus