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Literature summary for 3.1.1.13 extracted from
- Immunolocalization of a novel cholesteryl ester hydrolase in the endoplasmic reticulum of murine and human hepatocytes (2001), Hepatology, 33, 662-667.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | - |
Mus musculus | 5783 | - |
| endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
| microsome | - |
Mus musculus | - |
- |
| microsome | - |
Homo sapiens | - |
- |
| microsome | - |
Rattus norvegicus | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 106000 | - |
x * 106000, SDS-PAGE | Mus musculus |
| 106000 | - |
x * 106000, SDS-PAGE | Homo sapiens |
| 106000 | - |
x * 106000, SDS-PAGE | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| steryl ester + H2O = sterol + fatty acid | a group of enzymes of broad specificity, acting on esters of sterols and long-chain fatty acids, that may also bring about the esterification of sterols. Activated by bile salts | Mus musculus | |
| steryl ester + H2O = sterol + fatty acid | a group of enzymes of broad specificity, acting on esters of sterols and long-chain fatty acids, that may also bring about the esterification of sterols. Activated by bile salts | Homo sapiens | |
| steryl ester + H2O = sterol + fatty acid | a group of enzymes of broad specificity, acting on esters of sterols and long-chain fatty acids, that may also bring about the esterification of sterols. Activated by bile salts | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Hep-G2 cell | - |
Homo sapiens | - |
| hepatocyte | - |
Mus musculus | - |
| hepatocyte | - |
Homo sapiens | - |
| hepatocyte | - |
Rattus norvegicus | - |
| liver | - |
Mus musculus | - |
| liver | - |
Homo sapiens | - |
| liver | - |
Rattus norvegicus | - |
| additional information | no activity in nonparenchymal cells, no immunodetectable enzyme in microsomes of adrenal gland, ovary, testis, pancreas, intestine, white adipo tissue, mammary gland, lung, spleen, brain, aorta, and macrophage | Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cholesteryl oleate + H2O | - |
Mus musculus | cholesterol + oleate | - |
? |  |
| cholesteryl oleate + H2O | - |
Homo sapiens | cholesterol + oleate | - |
? | |
| cholesteryl oleate + H2O | - |
Rattus norvegicus | cholesterol + oleate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 106000, SDS-PAGE | Mus musculus |
| ? | x * 106000, SDS-PAGE | Homo sapiens |
| ? | x * 106000, SDS-PAGE | Rattus norvegicus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CEH | - |
Mus musculus |
| CEH | - |
Homo sapiens |
| CEH | - |
Rattus norvegicus |
| cholesteryl ester hydrolase | - |
Mus musculus |
| cholesteryl ester hydrolase | - |
Homo sapiens |
| cholesteryl ester hydrolase | - |
Rattus norvegicus |
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