Literature summary for 3.1.1.13 extracted from

Cook, K.G.; Lee, F.T.; Yeaman, S.J.
Hormone-sensitive cholesterol ester hydrolase of bovine adrenal cortex: identification of the enzyme protein (1981), FEBS Lett., 132, 10-14.

Search for more literature for 3.1.1.13

Inhibitors

Inhibitors	Comment	Organism	Structure
diisopropylfluorophosphate	modifies a serine residue at the active site	Bos taurus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
84000	-	SDS-PAGE, treatment with radio-labeled diisopropylfluorophosphonate	Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
cholesteryl esters + H2O	Bos taurus	important rate-limiting step in steroidogenesis	cholesterol + fatty acid	-	?

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
partial, 60fold, ultracentrifugation, chromatography steps	Bos taurus

Source Tissue

Source Tissue	Comment	Organism	Textmining
adrenal cortex	-	Bos taurus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.001	-	-	Bos taurus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
cholesteryl esters + H2O	important rate-limiting step in steroidogenesis	Bos taurus	cholesterol + fatty acid	-	?
cholesteryl oleate + H2O	-	Bos taurus	cholesterol + oleic acid	-	?
triacylglycerol + H2O	-	Bos taurus	diacylglycerol + carboxylic acid	-	?

Synonyms

Synonyms	Comment	Organism
hormone-sensitive cholesterol ester hydrolase	-	Bos taurus

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Release 2023.1 (January 2023)