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Literature summary for 3.1.1.1 extracted from
- Purification and characterization of a carboxylesterase from the intestine of the nematode Caenorhabditis elegans (1987), Biochemistry, 26, 4101-4107.
General Stability
| General Stability | Organism |
|---|---|
| 10% glycerol, increases stability | Caenorhabditis elegans |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Aldicarb | - |
Caenorhabditis elegans |  |
| Carbaryl | - |
Caenorhabditis elegans | |
| DFP | - |
Caenorhabditis elegans | |
| eserine | - |
Caenorhabditis elegans | |
| NaF | 5 mM, 50% inhibition | Caenorhabditis elegans | |
| Organophosphates | - |
Caenorhabditis elegans | |
| paraoxon | - |
Caenorhabditis elegans | |
| PMSF | 0.01-1 mM | Caenorhabditis elegans | |
| Trichlorfon | - |
Caenorhabditis elegans | |
| tris(p-nitrophenyl)phosphate | - |
Caenorhabditis elegans | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.008 | - |
1-naphthyl acetate | - |
Caenorhabditis elegans | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 60000 | - |
gel filtration | Caenorhabditis elegans |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Caenorhabditis elegans | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Caenorhabditis elegans |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| intestine | - |
Caenorhabditis elegans | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-naphthyl acetate + H2O | - |
Caenorhabditis elegans | 1-naphthol + acetate | - |
? | |
| 1-naphthyl propionate + H2O | - |
Caenorhabditis elegans | 1-naphthol + propionate | - |
? | |
| 2-naphthyl acetate + H2O | - |
Caenorhabditis elegans | 2-naphthol + acetate | - |
? | |
| 2-naphthyl propionate + H2O | - |
Caenorhabditis elegans | 2-naphthol + propionate | - |
? | |
| 4-methylumbelliferyl acetate + H2O | - |
Caenorhabditis elegans | 4-methylumbelliferone + acetate | - |
? | |
| 4-nitrophenyl acetate + H2O | - |
Caenorhabditis elegans | 4-nitrophenol + acetate | - |
? | |
| 4-nitrophenyl butyrate + H2O | - |
Caenorhabditis elegans | 4-nitrophenol + butyrate | - |
? | |
| aspirin + H2O | no activity | Caenorhabditis elegans | acetate + salicylate | - |
ir | |
| beta-thionaphthyl acetate + H2O | - |
Caenorhabditis elegans | beta-thionaphthol + acetate | - |
? | |
| phenyl acetate + H2O | - |
Caenorhabditis elegans | phenol + acetate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 60000, SDS-PAGE | Caenorhabditis elegans |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 500 | - |
1-naphthyl acetate | - |
Caenorhabditis elegans | |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 6 | 7.5 | most stable between pH 6.0 and 7.5, unstable at lower pH | Caenorhabditis elegans |
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