Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
O-phospho-L-seryl-tRNASec + selenophosphate + H2O | Homo sapiens | - |
L-selenocysteinyl-tRNASec + 2 phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9HD40 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
O-phospho-L-seryl-tRNASec + selenophosphate + H2O | - |
Homo sapiens | L-selenocysteinyl-tRNASec + 2 phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Selenocysteine synthase | - |
Homo sapiens |
SepSecS | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
metabolism | in mammalian cells, the incorporation of the 21st amino acid, selenocysteine, into proteins is guided by the Sec machinery. The function of this protein complex requires several protein?protein and protein?RNA interactions, leading to the incorporation of selenocysteine at UGA codons. It is guided by stem?loop structures localized in the 3? untranslated regions of the selenoprotein-encoding genes | Homo sapiens |