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Literature summary for 2.8.3.16 extracted from

  • Azcarate-Peril, M.A.; Bruno-Barcena, J.M.; Hassan, H.M.; Klaenhammer, T.R.
    Transcriptional and functional analysis of oxalyl-coenzyme A (CoA) decarboxylase and formyl-CoA transferase genes from Lactobacillus acidophilus (2006), Appl. Environ. Microbiol., 72, 1891-1899.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.8.3.16

Activating Compound

Activating Compound Comment Organism Structure
additional information oxalate induces the expression of genes frc and oxc Lactobacillus acidophilus

Cloned(Commentary)

Cloned (Comment) Organism
gene frc, DNA and amino acid sequence determination and analysis, phylogenetic analysis Lactobacillus gasseri
gene frc, DNA and amino acid sequence determination and analysis, phylogenetic analysis Bifidobacterium animalis subsp. lactis
gene frc, organized in the oxc operon, DNA and amino acid sequence determination and analysis, transcriptional and quantitative expression analysis, mildly acidic conditions are a prerequisite for frc and oxc transcription, phylogenetic analysis Lactobacillus acidophilus

Protein Variants

Protein Variants Comment Organism
additional information construction of a frc deletion mutant, frc expression specifically improves survival in the presence of oxalic acid at pH 3.5, the frc mutant is unable to degrade oxalate, phenotype, overview Lactobacillus acidophilus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
formyl-CoA + oxalate Lactobacillus acidophilus the enzyme is required for oxalate degradation together with oxalyl-CoA decarboxylase, EC 4.1.1.8, overview formate + oxalyl-CoA
-
 ?
formyl-CoA + oxalate Lactobacillus acidophilus NCFM the enzyme is required for oxalate degradation together with oxalyl-CoA decarboxylase, EC 4.1.1.8, overview formate + oxalyl-CoA
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 ?

Organism

Organism UniProt Comment Textmining
Bifidobacterium animalis subsp. lactis
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 gene frc
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Lactobacillus acidophilus
-
-
-
Lactobacillus acidophilus NCFM
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-
-
Lactobacillus gasseri
-
 gene frc
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
formyl-CoA + oxalate
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 Lactobacillus acidophilus formate + oxalyl-CoA
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 ?
formyl-CoA + oxalate the enzyme is required for oxalate degradation together with oxalyl-CoA decarboxylase, EC 4.1.1.8, overview Lactobacillus acidophilus formate + oxalyl-CoA
-
 ?
formyl-CoA + oxalate
-
 Lactobacillus acidophilus NCFM formate + oxalyl-CoA
-
 ?
formyl-CoA + oxalate the enzyme is required for oxalate degradation together with oxalyl-CoA decarboxylase, EC 4.1.1.8, overview Lactobacillus acidophilus NCFM formate + oxalyl-CoA
-
 ?