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Literature summary for 2.8.2.9 extracted from

  • Chung, K.H.; Ringer, D.P.; Shin, K.O.
    Effects of copper, zinc and cadmium on the recovery pattern of aryl sulfotransferase IV activity in rats fed 2-acetylaminoflourene diet (2006), Nutr. Sci., 9, 29-34.
No PubMed abstract available
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Inhibitors

Inhibitors Comment Organism Structure
2-acetylaminofluorene increases and/or alters the inhibitory effect of metal ions, relationship between inhibition by heavy metal ions and dietary 2-acetylaminofluorene, overview Rattus norvegicus
Cd2+ strong inhibition in vitro and in vivo, 50% inhibition of purified enzyme at about 0.0025 mM, 50% inhibition in liver cytosol at about 0.025 mM Rattus norvegicus
Cu2+ elevated copper levels in the diet result in reduced enzyme levels in rat liver, strong inhibition in vitro and in vivo, 50% inhibition of purified enzyme at about 0.0025 mM, 50% inhibition in liver cytosol at about 0.025 mM Rattus norvegicus
terbium
-
 Rattus norvegicus
Zn2+ indirect inhibition mechanism, strong inhibition in vitro and in vivo, 50% inhibition of purified enzyme at about 0.0025 mM, 50% inhibition in liver cytosol at about 0.025 mM Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Synonyms

Synonyms Comment Organism
aryl sulfotransferase IV
-
 Rattus norvegicus
AST IV
-
 Rattus norvegicus