Cloned (Comment) | Organism |
---|---|
overexpression of the bifunctional enzyme in CHO cells | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3',5'-ADP | - |
Rattus norvegicus | |
additional information | NEM: no effect | Rattus norvegicus | |
NaCl | above 200 mM | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
Golgi vesicle | lumen | Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine | Rattus norvegicus | N-sulfated residues of heparan sulfate participate in the binding of this polymer to proteins as basic fibroblast growth factor | adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
a single protein possesses both N-deacetylase and N-sulfotransferase activity | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine | substrate needs to be deacetylated | Rattus norvegicus | adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine | - |
? | |
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine | N-sulfated residues of heparan sulfate participate in the binding of this polymer to proteins as basic fibroblast growth factor | Rattus norvegicus | adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine | - |
? | |
3'-phosphoadenylylsulfate + heparan sulfate | - |
Rattus norvegicus | adenosine 3',5'-bisphosphate + N-sulfoheparan sulfate | - |
? |