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Literature summary for 2.8.2.5 extracted from
- Molecular cloning and characterization of chondroitin-4-O-sulfotransferase-3. A novel member of the HNK-1 family of sulfotransferases (2002), J. Biol. Chem., 277, 34766-34772.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| protamine | stimulates | Homo sapiens |  |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| DNA sequence determination and analysis, located on chromosome 3, genomic organisation, expression as myc- and His-tagged enzyme in CHO cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q9NPF2 | isozyme C4ST1 | - |
| Homo sapiens | Q9NRB3 | isozyme C4ST2 | - |
| Homo sapiens | Q8NET6 | isozyme C4ST3 | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant His-tagged isozyme C4ST3 from CHO cells | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | low content | Homo sapiens | - |
| liver | isozyme C4ST3, high content in adult, low content in fetal liver | Homo sapiens | - |
| lymph node | - |
Homo sapiens | - |
| lymph node | isozyme C4ST, low content | Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylylsulfate + chondroitin | - |
Homo sapiens | adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate | - |
? | |
| 3'-phosphoadenylylsulfate + desulfated dermatan sulfate | - |
Homo sapiens | ? | - |
? | |
| 3'-phosphoadenylylsulfate + desulfated dermatan sulfate | i.e. dermatan | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| C4ST | - |
Homo sapiens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 28 | - |
assay at | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | - |
- |
Homo sapiens |
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