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Literature summary for 2.8.2.5 extracted from

  • Hiraoka, N.; Nakagawa, H.; Ong, E.; Akama, T.O.; Fukuda, M.N.; Fukuda, M.
    Molecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family (2000), J. Biol. Chem., 275, 20188-20196.
    View publication on PubMed
Search for more literature for 2.8.2.5

Cloned(Commentary)

Cloned (Comment) Organism
DNA sequence determination and analysis, chromosome mapping at p22 region of chromosome 7, expression in CHO cells Homo sapiens
DNA sequence dtermination and analysis, chromosome mapping at q23 region of chromosome 12, expression in CHO cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus
-
 Homo sapiens 5794
-

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9NPF2 isozyme C4ST1
-
Homo sapiens Q9NRB3 isozyme C4ST2
-

Source Tissue

Source Tissue Comment Organism Textmining
leukocyte isozyme C4ST1 expression Homo sapiens
-
lung adult and fetal Homo sapiens
-
lung isozyme C4ST2 expression Homo sapiens
-
lung isozyme C4ST1 expression Homo sapiens
-
lymph node isozyme C4ST1 expression Homo sapiens
-
peripheral blood mononuclear cell
-
 Homo sapiens
-
pituitary gland isozyme C4ST2 expression Homo sapiens
-
placenta isozyme C4ST1 expression Homo sapiens
-
prostate isozyme C4ST2 expression Homo sapiens
-
small intestine isozyme C4ST2 expression Homo sapiens
-
spinal cord isozyme C4ST2 expression Homo sapiens
-
spleen isozyme C4ST2 expression Homo sapiens
-
spleen isozyme C4ST1 expression Homo sapiens
-
thymus isozyme C4ST1 expression Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylylsulfate + chondroitin
-
 Homo sapiens adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate
-
 ?
3'-phosphoadenylylsulfate + chondroitin sulfate C
-
 Homo sapiens adenosine 3',5'-bisphosphate + chondroitin sulfate C 4'-sulfate
-
 ?
3'-phosphoadenylylsulfate + desulfated chondroitin sulfate A
-
 Homo sapiens adenosine 3',5'-bisphosphate + chondroitin sulfate A
-
 ?
3'-phosphoadenylylsulfate + desulfated dermatan sulfate
-
 Homo sapiens ?
-
 ?
additional information no activity with dermatan sulfate, keratan sulfate Homo sapiens ?
-
 ?
additional information no activity with desulfated and N-sulfated heparin, and desulfated and N-acetylated heparin Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
C4ST
-
 Homo sapiens
chondroitin 4-O-sulfotransferase
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8
-
 assay at Homo sapiens