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Literature summary for 2.8.2.34 extracted from
- Purification of human fetal hepatic bile acid sulfotransferase (BAST) (1992), Biochem. Soc. Trans., 20, 167S.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Homo sapiens | 5829 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 65000 | - |
x * 65000, SDS-PAGE | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylyl 5'-phosphosulfate + lithocholate | Homo sapiens | - |
adenosine 3',5'-bisphosphate + lithocholate 3-sulfate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| from foetal liver cytosol, 760fold, ion exchange chromatography, adenosine 3',5'-bisphosphate affinity chromatography, and gel filtration, overview | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | foetal | Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.018 | - |
purified enzyme | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylyl 5'-phosphosulfate + dehydroepiandrosterone | i.e. androst-5-ene-3beta-ol-17-one | Homo sapiens | adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
? | |
| 3'-phosphoadenylyl 5'-phosphosulfate + lithocholate | - |
Homo sapiens | adenosine 3',5'-bisphosphate + lithocholate 3-sulfate | - |
? | |
| additional information | substrate specificity of enzyme purified in different ways, overview | Homo sapiens | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 65000, SDS-PAGE | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BAST | - |
Homo sapiens |
| bile acid sulfotransferase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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