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Literature summary for 2.8.2.30 extracted from

  • O'Donnell, C.D.; Tiwari, V.; Oh, M.; Shukla, D.
    A role for heparan sulfate 3-O-sulfotransferase isoform 2 in herpes simplex virus type 1 entry and spread (2006), Virology, 346, 452-459.
    View publication on PubMed
Search for more literature for 2.8.2.30

Cloned(Commentary)

Cloned (Comment) Organism
3-OST-3, transient expression in CHO-K1 cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information expression of 3-OST-3 leads to cell-to-cll fusion activity in CHO-K1 cells via gD receptors modified with 3-OS HS generated by 3-OST-3, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine Homo sapiens 3-OST-3 is involved in 3-OST-2-mediated HSV-1 entry into cells by catalyzing the preceeding step of 3-O-sulfated heparin sulfate modification of receptors adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine
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 Homo sapiens adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate
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 ?
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine 3-OST-3 is involved in 3-OST-2-mediated HSV-1 entry into cells by catalyzing the preceeding step of 3-O-sulfated heparin sulfate modification of receptors Homo sapiens adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate
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 ?

Synonyms

Synonyms Comment Organism
3-O-sulfotransferase-3
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 Homo sapiens
3-OST-3
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 Homo sapiens
heparan sulfate 3-O-sulfotransferase 3
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 Homo sapiens
HS 3-OST-3
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 Homo sapiens