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Literature summary for 2.8.2.3 extracted from

  • Maritomi, Y.; Niwa, T.; Shiraga, T.; Iwasaki, K.; Noda, K.
    Isolation and characterization of an alicyclic amine N-sulfotransferase from female rat liver (1994), Biol. Pharm. Bull., 17, 1008-1011.
    View publication on PubMed
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KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.382
-
 4-phenyl-1,2,3,6-tetrahydropyridine
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylylsulfate + 2-naphthylamine Rattus norvegicus
-
 adenosine 3',5'-bisphosphate + 2-naphthylsulfamate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 female
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.236
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylylsulfate + 2-naphthylamine
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + 2-naphthylsulfamate
-
 ?
3'-phosphoadenylylsulfate + 2-naphthylamine poor substrate Rattus norvegicus adenosine 3',5'-bisphosphate + 2-naphthylsulfamate
-
 ?
3'-phosphoadenylylsulfate + 4-phenyl-1,2,3,6-tetrahydropyridine
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + 4-phenyl-1,2,3,6-tetrahydropyridine N-sulfate
-
 ?
3'-phosphoadenylylsulfate + dehydroepiandrosterone
-
 Rattus norvegicus ?
-
 ?
3'-phosphoadenylylsulfate + tyramine
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + tyramine N-sulfate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 two optima: pH 7.4 and pH 10, activity towards alicyclic amines is higher at pH 10 Rattus norvegicus
10
-
 two optima: pH 7.4 and pH 10, activity towards alicyclic amines is higher at pH 10 Rattus norvegicus