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Literature summary for 2.8.2.22 extracted from

  • Kobashi, K.; Kim, D.H.; Morikawa, T.
    A novel type of arylsulfotransferase (1987), J. Protein Chem., 6, 237-244.
No PubMed abstract available

Activating Compound

Activating Compound Comment Organism Structure
Diethyldithiocarbamic acid sodium salt
-
Eubacterium sp.
tosyl-L-Lys chloromethyl ketone
-
Eubacterium sp.

Metals/Ions

Metals/Ions Comment Organism Structure
additional information ineffective: Ca2+, Ba2+ Eubacterium sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
80000
-
4 * 80000 Eubacterium sp.
315000
-
-
Eubacterium sp.

Organism

Organism UniProt Comment Textmining
Eubacterium sp.
-
A-44
-
Eubacterium sp. A-44
-
A-44
-

Purification (Commentary)

Purification (Comment) Organism
-
Eubacterium sp.

Reaction

Reaction Comment Organism Reaction ID
an aryl sulfate + a phenol = a phenol + an aryl sulfate mechanism Eubacterium sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-acetylphenyl sulfate + tyramine best donor with tyramine as acceptor Eubacterium sp. 4-(2-aminoethyl)phenyl sulfate + 4-acetylphenol
-
?
4-methylumbelliferyl sulfate + tyramine
-
Eubacterium sp. 4-(2-aminoethyl)phenyl sulfate + 4-methylumbelliferol
-
?
4-nitrophenyl sulfate + alpha-naphthol best acceptor with p-nitrophenol as donor Eubacterium sp. 4-nitrophenol + 1-naphththyl sulfate
-
?
4-nitrophenyl sulfate + alpha-naphthol best acceptor with p-nitrophenol as donor Eubacterium sp. A-44 4-nitrophenol + 1-naphththyl sulfate
-
?
4-nitrophenyl sulfate + epinephrine
-
Eubacterium sp. ? + 4-nitrophenol
-
?
4-nitrophenyl sulfate + epinephrine
-
Eubacterium sp. A-44 ? + 4-nitrophenol
-
?
4-nitrophenyl sulfate + estradiol
-
Eubacterium sp. estradiol sulfate + 4-nitrophenol
-
?
4-nitrophenyl sulfate + estradiol
-
Eubacterium sp. A-44 estradiol sulfate + 4-nitrophenol
-
?
4-nitrophenyl sulfate + phenol
-
Eubacterium sp. phenyl sulfate + 4-nitrophenol
-
?
4-nitrophenyl sulfate + tyramine
-
Eubacterium sp. 4-(2-aminoethyl)phenyl sulfate + 4-nitrophenol
-
?
additional information only the 4-position of catecholamines is specifically sulfated, naturally occuring phenolic compounds, e.g. flavine, chalcone, xanthone are sulfated, tyrosine-containing peptides, e.g. enkephalin, LH-RH, vasopressin, angiotensin, proctorin, cholecystokinin octopeptide, phyllocerulein are sulfated with high yield, hydroxyl groups of tyrosine residues in peptides such as angiotensin can act as acceptors, does not act on 3'-phosphoadenylylsulfate or adenosine 3',5'-bisphosphate Eubacterium sp. ?
-
?
additional information only the 4-position of catecholamines is specifically sulfated, naturally occuring phenolic compounds, e.g. flavine, chalcone, xanthone are sulfated, tyrosine-containing peptides, e.g. enkephalin, LH-RH, vasopressin, angiotensin, proctorin, cholecystokinin octopeptide, phyllocerulein are sulfated with high yield, hydroxyl groups of tyrosine residues in peptides such as angiotensin can act as acceptors, does not act on 3'-phosphoadenylylsulfate or adenosine 3',5'-bisphosphate Eubacterium sp. A-44 ?
-
?
phenyl sulfate + an aryl alcohol
-
Eubacterium sp. phenol + an aryl sulfate
-
?
phenyl sulfate + an aryl alcohol
-
Eubacterium sp. A-44 phenol + an aryl sulfate
-
?

Subunits

Subunits Comment Organism
tetramer 4 * 80000 Eubacterium sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8 9
-
Eubacterium sp.