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BRENDA support

Literature summary for 2.8.2.14 extracted from

  • Barnes, S.; Waldrop, R.; Crenshaw, J.; King, R.J.; Taylor, K.B.
    Evidence for an ordered reaction mechanism for bile salt:3phosphoadenosine-5-phosphosulfate:sulfotransferase from rhesus monkey liver that catalyzes the sulfation of the hepatotoxin glycolithocholate (1986), J. Lipid Res., 27, 1111-1123.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
3-keto-5-beta-cholanoate competitive inhibitor of glycolithocholate Macaca mulatta

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Macaca mulatta 5829
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ no absolute requirement, stimulated by low concentrations below 2.0 mM Macaca mulatta

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
SDS-PAGE Macaca mulatta

Organism

Organism UniProt Comment Textmining
Macaca mulatta
-
rhesus monkey
-

Purification (Commentary)

Purification (Comment) Organism
-
Macaca mulatta

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Macaca mulatta
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl-sulfate + glycolithocholate
-
Macaca mulatta adenosine 3',5'-bisphosphate + glycolithocholate 3-sulfate
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
-
Macaca mulatta