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Literature summary for 2.8.2.1 extracted from

  • Saruwatari, A.; Okamura, S.; Nakajima, Y.; Narukawa, Y.; Takeda, T.; Tamura, H.
    Pomegranate juice inhibits sulfoconjugation in Caco-2 human colon carcinoma cells (2008), J. Med. Food, 11, 623-628.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
punicalagin
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Caco-2 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylylsulfate + 1-naphthol
-
Homo sapiens adenosine 3',5'-bisphosphate + 1-naphthyl sulfate
-
?

Synonyms

Synonyms Comment Organism
sulfotransferase
-
Homo sapiens
SULT1A1
-
Homo sapiens
SULT1A3
-
Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.045
-
in 10 mM phosphate buffer (pH 7.4), at 37°C Homo sapiens punicalagin

Expression

Organism Comment Expression
Homo sapiens pomegranate juice shows no effects on the expression of the sulfotransferase SULT1A family of genes (SULT1A1 and SULT1A3) in Caco-2 cells additional information