Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-hydroxy-4-ethylbenzene | - |
Homo sapiens | |
2-Ethylphenol | inhibits SULT1A1/2 and SULT1A3 | Homo sapiens | |
2-n-propylphenol | inhibits SULT1A1/2, but not SULT1A3 | Homo sapiens | |
2-sec-Butylphenol | inhibits SULT1A1/2, but not SULT1A3 | Homo sapiens | |
2-sec-propylphenol | inhibits SULT1A1/2 and SULT1A3 | Homo sapiens | |
2-tert-butylphenol | inhibits SULT1A1/2, but not SULT1A3 | Homo sapiens | |
4-n-amylphenol | inhibits SULT1A1/2, but not SULT1A3 | Homo sapiens | |
4-n-heptylphenol | inhibits SULT1A1/2, but not SULT1A3 | Homo sapiens | |
4-n-nonylphenol | inhibits SULT1A1/2, but not SULT1A3 | Homo sapiens | |
4-n-octylphenol | inhibits SULT1A1/2, but not SULT1A3 | Homo sapiens | |
4-nitrophenol | SULT1A1/2 | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetics | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
SULT1A1/2, a P-PST enzyme form | - |
Homo sapiens | - |
2 forms: simple phenol sulfating P-PST, monoamine sulfating M-PST | - |
Homo sapiens | - |
SULT1A3, is a M-PST enzyme form | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
platelet | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + a phenol | SULT1A1/2: preference for straight chain phenol substrates with C1-2 and C4-5 chain lengths, overview | Homo sapiens | adenosine 3',5'-bisphosphate + an aryl sulfate | - |
? | |
3'-phosphoadenylyl sulfate + a phenol | SULT1A3 is not active with short chain alkylphenols | Homo sapiens | adenosine 3',5'-bisphosphate + an aryl sulfate | - |
? | |
3'-phosphoadenylylsulfate + 2-ethylphenol | SULT1A1/2 | Homo sapiens | adenosine 3',5'-bisphosphate + 2-ethylphenyl sulfate | - |
? | |
3'-phosphoadenylylsulfate + 2-methylphenol | SULT1A1/2 | Homo sapiens | adenosine 3',5'-bisphosphate + 2-methylphenyl sulfate | - |
? | |
3'-phosphoadenylylsulfate + 3-ethylphenol | SULT1A1/2 | Homo sapiens | adenosine 3',5'-bisphosphate + 3-ethylphenyl sulfate | - |
? | |
3'-phosphoadenylylsulfate + 3-methylphenol | SULT1A1/2 | Homo sapiens | adenosine 3',5'-bisphosphate + 3-methylphenyl sulfate | - |
? | |
3'-phosphoadenylylsulfate + 4-ethylphenol | SULT1A1/2 | Homo sapiens | adenosine 3',5'-bisphosphate + 4-ethylphenyl sulfate | - |
? | |
3'-phosphoadenylylsulfate + 4-methylphenol | SULT1A1/2 | Homo sapiens | adenosine 3',5'-bisphosphate + 4-methylphenyl sulfate | - |
? | |
3'-phosphoadenylylsulfate + 4-n-amylphenol | SULT1A1/2 | Homo sapiens | adenosine 3',5'-bisphosphate + 4-n-amylphenyl sulfate | - |
? | |
3'-phosphoadenylylsulfate + 4-n-butylphenol | SULT1A1/2 | Homo sapiens | adenosine 3',5'-bisphosphate + 4-n-butylphenyl sulfate | - |
? | |
3'-phosphoadenylylsulfate + 4-n-propylphenol | SULT1A1/2 | Homo sapiens | adenosine 3',5'-bisphosphate + 4-n-propylphenyl sulfate | - |
? | |
3'-phosphoadenylylsulfate + 4-nitrophenol | SULT1A1/2 | Homo sapiens | adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate | - |
? | |
3'-phosphoadenylylsulfate + dopamine | SULT1A3 | Homo sapiens | adenosine 3',5'-bisphosphate + ? | - |
? | |
additional information | substrate specificity | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SULT | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0052 | - |
4-nitrophenol | SULT1A1/2, pH 7.0, 37°C | Homo sapiens | |
0.0123 | - |
1-hydroxy-4-ethylbenzene | SULT1A1/2, pH 7.0, 37°C | Homo sapiens | |
0.0151 | - |
4-n-amylphenol | SULT1A1/2, pH 7.0, 37°C | Homo sapiens |