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Literature summary for 2.8.2.1 extracted from

  • Tong, Z.; James, M.O.
    Purification and characterization of hepatic and intestinal phenol sulfotransferase with high affinity for benzo[a]pyrene phenols from channel catfish, Ictalurus punctatus (2000), Arch. Biochem. Biophys., 376, 409-419.
    View publication on PubMed
Search for more literature for 2.8.2.1

Inhibitors

Inhibitors Comment Organism Structure
hydroxybenzo[a]pyrenes substrate inhibition above 0.0005 mM Ictalurus punctatus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information kinetics Ictalurus punctatus
additional information
-
 additional information Km for 3'-phosphoadenylylsulfate with several substrates, liver and intestinal enzyme Ictalurus punctatus
0.000036
-
 9-hydroxybenzo[a]pyrene liver enzyme, pH 7.0, 35°C Ictalurus punctatus
0.000041
-
 9-hydroxybenzo[a]pyrene intestinal enzyme, pH 7.0, 35°C Ictalurus punctatus
0.000053
-
 3-Hydroxybenzo[a]pyrene liver enzyme, pH 7.0, 35°C Ictalurus punctatus
0.000069
-
 3-Hydroxybenzo[a]pyrene intestinal enzyme, pH 7.0, 35°C Ictalurus punctatus
0.000125
-
 7-hydroxybenzo[a]pyrene intestinal enzyme, pH 7.0, 35°C Ictalurus punctatus
0.000126
-
 7-hydroxybenzo[a]pyrene liver enzyme, pH 7.0, 35°C Ictalurus punctatus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Ictalurus punctatus 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
41000
-
 x * 41000, SDS-PAGGE Ictalurus punctatus

Organism

Organism UniProt Comment Textmining
Ictalurus punctatus
-
 channel catfish
-

Purification (Commentary)

Purification (Comment) Organism
335fold from liver and 287fold from intestinal mucosa Ictalurus punctatus

Source Tissue

Source Tissue Comment Organism Textmining
intestine mucosa Ictalurus punctatus
-
liver
-
 Ictalurus punctatus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + a phenol
-
 Ictalurus punctatus adenosine 3',5'-bisphosphate + an aryl sulfate
-
 ?
3'-phosphoadenylylsulfate + 2-naphthol
-
 Ictalurus punctatus adenosine 3',5'-bisphosphate + 2-naphthyl sulfate
-
 ?
3'-phosphoadenylylsulfate + 3-hydroxybenzo[a]pyrene
-
 Ictalurus punctatus adenosine 3',5'-bisphosphate + benzo[a]pyrene 3-sulfate
-
 ?
3'-phosphoadenylylsulfate + 4-methylumbelliferone
-
 Ictalurus punctatus adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylylsulfate + 4-nitrophenol
-
 Ictalurus punctatus adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
 ?
3'-phosphoadenylylsulfate + 7-(hydroxymethyl)-12-methylbenz[a]anthracene
-
 Ictalurus punctatus adenosine 3',5'-bisphosphate + sulfuric acid mono-(12-methyl-benzo[a]anthracen-7ylmethyl)ester
-
 ?
3'-phosphoadenylylsulfate + 7-hydroxybenzo[a]pyrene
-
 Ictalurus punctatus adenosine 3',5'-bisphosphate + benzo[a]pyrene 7-sulfate
-
 ?
3'-phosphoadenylylsulfate + 9-hydroxybenzo[a]pyrene
-
 Ictalurus punctatus adenosine 3',5'-bisphosphate + benzo[a]pyrene 9-sulfate
-
 ?
additional information substrate specificity Ictalurus punctatus ?
-
 ?

Subunits

Subunits Comment Organism
? x * 41000, SDS-PAGGE Ictalurus punctatus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
35
-
 assay at Ictalurus punctatus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 assay at Ictalurus punctatus