Literature summary for 2.8.1.12 extracted from

Narrandes, N.C.; Machowski, E.E.; Mizrahi, V.; Kana, B.D.
Cleavage of the moaX-encoded fused molybdopterin synthase from Mycobacterium tuberculosis is necessary for activity (2015), BMC Microbiol., 15, 22.

Search for more literature for 2.8.1.12

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Mycobacterium tuberculosis

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
10000	-	-	Mycobacterium tuberculosis
17000	-	-	Mycobacterium tuberculosis

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
cyclic pyranopterin phosphate + [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + H2O	Mycobacterium tuberculosis	-	molybdopterin + molybdopterin-synthase sulfur-carrier protein	-	?

Organism

Organism	UniProt	Comment	Textmining
Mycobacterium tuberculosis	Q6MWY3	carrier subunit MoaX	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
cyclic pyranopterin phosphate + [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + H2O	-	Mycobacterium tuberculosis	molybdopterin + molybdopterin-synthase sulfur-carrier protein	-	?

Subunits

Subunits	Comment	Organism
heterotetramer	2 * 17000 + 2 * 10000, SDS-PAGE	Mycobacterium tuberculosis

Synonyms

Synonyms	Comment	Organism
MoaD	subunit	Mycobacterium tuberculosis
MoaE	catalytic subunit	Mycobacterium tuberculosis
MoaX	carrier subunit	Mycobacterium tuberculosis
MPT synthase	-	Mycobacterium tuberculosis
Rv3323c	-	Mycobacterium tuberculosis

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)