Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
1.04 A resolution crystal structure displays an exposed active site that is distinct from that of rhodanese and mercaptopyruvate sulfurtransferase | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.017 | - |
thioredoxin | 37°C, pH 7.4 | Homo sapiens | |
0.27 | - |
cyanide | 37°C, pH 7.4 | Homo sapiens | |
22 | - |
thiosulfate | cosubstrate cyanide, 37°C, pH 7.4 | Homo sapiens | |
22 | - |
thiosulfate | cosubstrate thioredoxin, 37°C, pH 7.4 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q8NFU3 | cf. EC 2.8.1.3 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colon | apical localization in colonic crypts | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
2.6 | - |
pH 7.4, 37°C | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
thiosulfate + 2 glutathione | - |
Homo sapiens | sulfite + glutathione disulfide + sulfide | - |
? | |
thiosulfate + cyanide | - |
Homo sapiens | sulfite + thiocyanate | - |
? | |
thiosulfate + thioredoxin | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TSTD1 | - |
Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.52 | - |
cyanide | 37°C, pH 7.4 | Homo sapiens |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.94 | - |
cyanide | 37°C, pH 7.4 | Homo sapiens |