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Literature summary for 2.7.99.1 extracted from

  • Tsutsui, K.
    Tripolyphosphate is an alternative phosphodonor of the selective protein phosphorylation of liver microsomal membrane (1986), J. Biol. Chem., 261, 2645-2653.
    View publication on PubMed
Search for more literature for 2.7.99.1

Inhibitors

Inhibitors Comment Organism Structure
5'-adenylimidodiphosphate i.e. AMP-PNP, ATP analogue Rattus norvegicus
adenosine 5'-(beta,gamma-Imino)triphosphate i.e. AMP-PNP, ATP analogue Rattus norvegicus
adenosine 5'-(beta,gamma-methylene)triphosphate i.e. AMP-PCP or AMP-CPP, ATP analogue Rattus norvegicus
adenosine 5'-methylene diphosphate i.e. AMP-CP, ATP analogue Rattus norvegicus
ADP
-
 Rattus norvegicus
ATP
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Rattus norvegicus 16020
-
microsome
-
 Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
triphosphate + [microsomal membrane protein] Rattus norvegicus reversible phosphorylation in the second phase of membrane protein phosphorylation, competes with ATP-dependent phosphorylation reaction which occurs in the first phase diphosphate + phosphorylated [microsomal membrane protein]
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
from liver microsomal membranes by DEAE ion exchange chromatography and gel filtration Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
tetraphosphate + [microsomal membrane protein] reversible phosphorylation, substrates are 145 kD and 130 kD microsomal membrane proteins, higher activity compared to triphosphate as phosphate donor Rattus norvegicus triphosphate + phosphorylated [microsomal membrane protein]
-
 ?
triphosphate + [microsomal membrane protein] reversible phosphorylation in the second phase of membrane protein phosphorylation, competes with ATP-dependent phosphorylation reaction which occurs in the first phase Rattus norvegicus diphosphate + phosphorylated [microsomal membrane protein]
-
 ?
triphosphate + [microsomal membrane protein] reversible phosphorylation, substrates are 145 kD and 130 kD microsomal membrane proteins Rattus norvegicus diphosphate + phosphorylated [microsomal membrane protein]
-
 ?