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Literature summary for 2.7.9.3 extracted from

  • Morey, M.; Serras, F.; Corominas, M.
    Halving the selenophosphate synthetase gene dose confers hypersensitivity to oxidative stress in Drosophila melanogaster (2003), FEBS Lett., 534, 111-114.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
overexpression of the wild-type enzyme in motoneurons does not extend longevity Drosophila melanogaster

Protein Variants

Protein Variants Comment Organism
additional information selD mutant SelDptuf is less resistant to reactive oxygen species, paraquat and H2O2, compared to the wild-type Drosophila melanogaster

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + selenide + H2O Drosophila melanogaster involved in synthesis of selenoproteins, that provide protection against oxidative stress by acting as cellular antioxidants AMP + selenophosphate + phosphate
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Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
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gene selD
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + selenide + H2O involved in synthesis of selenoproteins, that provide protection against oxidative stress by acting as cellular antioxidants Drosophila melanogaster AMP + selenophosphate + phosphate
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