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Literature summary for 2.7.9.1 extracted from

  • Acosta, H.; Dubourdieu, M.; Quinones, W.; Caceres, A.; Bringaud, F.; Concepcion, J.L.
    Pyruvate phosphate dikinase and pyrophosphate metabolism in the glycosome of Trypanosoma cruzi epimastigotes (2004), Comp. Biochem. Physiol. B, 138, 347-356.
    View publication on PubMed
Search for more literature for 2.7.9.1

Localization

Localization Comment Organism GeneOntology No. Textmining
glycosome matrix Trypanosoma cruzi 20015
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
AMP + phosphoenolpyruvate + diphosphate Trypanosoma cruzi the enzyme likely works in the direction of pyruvate production. PPDK is a central enzyme in the metabolism of glycosome by providing a link between glycolysis fatty acid oxidation and biosynthetic diphosphate-producing pathways. PPDK seems to replace diphosphatase in its classical thermodynamic role of displacing the equilibrium of diphosphate-producing reactions, as well as in its role of eliminating the toxic diphosphate ATP + pyruvate + phosphate
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 r

Organism

Organism UniProt Comment Textmining
Trypanosoma cruzi
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-
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Source Tissue

Source Tissue Comment Organism Textmining
epimastigote
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 Trypanosoma cruzi
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
AMP + phosphoenolpyruvate + diphosphate the enzyme likely works in the direction of pyruvate production. PPDK is a central enzyme in the metabolism of glycosome by providing a link between glycolysis fatty acid oxidation and biosynthetic diphosphate-producing pathways. PPDK seems to replace diphosphatase in its classical thermodynamic role of displacing the equilibrium of diphosphate-producing reactions, as well as in its role of eliminating the toxic diphosphate Trypanosoma cruzi ATP + pyruvate + phosphate
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 r

Synonyms

Synonyms Comment Organism
PPDK
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 Trypanosoma cruzi